Originating in Buenos Aires, Avellaneda, 1987 as a HCxBA group composed of [a=Juan Fandiño], [a=Fernando Cordera] and two other friends that left after a few months. In early 1988 Ricky Espinosa, [a=Alejandro Alsina] and [a=Sebastián Corona] join. Flema saw it's debut on [url=508520]Invasión 88[/url], followed by a demo. By the end of 1989, the group disbands.

Espinosa met and befriended [a=Santiago Rossi] and [a=Fernando Rossi], together they reformed the group as a trio and then quartet with a returning Alsina. Releases Pogo, Mosh y Slam and Nunca Nos Fuimos scored them unexpected city-wide notoriety.
Extreme popularity led to problems at concerts and Flema found itself unable to play due to lack of venues around 1997. A side project by Espinosa, Flemita, was formed during this period.

The group disbanded a few months after Espinosa's accidental death in late 2002. In 2007 it reformed for a 20 years concert which developed into an international tour and a return to activity.